Forensic Science International: Genetics – Table of contents

Forensic Science International: Genetics

January 2015, volume 14

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Quality of biopsy directly linked to survival in bladder cancer patients

EurekAlert 22 October 2014

UCLA researchers have shown for the first time that the quality of diagnostic staging using biopsy in patients with bladder cancer is directly linked with survival, meaning those that don’t get optimal biopsies are more likely to die from their disease.

The two-year study found that about half of bladder cancer patients who were biopsied had insufficient material – meaning there was no bladder wall muscle retrieved – to accurately stage the cancer. Additionally, the UCLA research team found that a suboptimal biopsy and incorrect tumor staging was associated with a significant increase in deaths from bladder cancer, said study first author Dr. Karim Chamie, an assistant professor of urology and surgical director of the bladder cancer program at UCLA.

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Skin patch could replace the syringe for disease diagnosis

EurekAlert 22 October 2014

Drawing blood and testing it is standard practice for many medical diagnostics. As a less painful alternative, scientists are developing skin patches that could one day replace the syringe. In the ACS journal Analytical Chemistry, one team reports they have designed and successfully tested, for the first time, a small skin patch that detected malaria proteins in live mice. It could someday be adapted for use in humans to diagnose other diseases, too.

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Russia will not destroy smallpox virus

BioPrepWatch 17 October 2014

Pending the decision of the World Health Organization (WHO) to destroy smallpox virus stocks, the Russian State Research Center of Virology and Biotechnology (VECTOR) will not eliminate its stocks prematurely.

Y chromosome linked to cancer and death risk in men

BBC News 22 October 2014

The male Y chromosome may have a role in prolonging men’s lives and fighting cancer, scientists have said.

Research into 1,153 elderly men at the University of Sweden found those who had lost part of their Y chromosome died on average 5.5 years earlier than those who had not.

Women live on average 7.5 years longer than men in Europe and the reasons behind this are not fully known.

Cancer Research said the study was “intriguing”.

Scientists assessed how many blood cells had age-related loss of the Y chromosome (LOY) through blood tests in the men, aged between 70 and 84.

WHO revises global tuberculosis estimate up by 500,000

BBC news 22 October 2014

In 2013 nine million people had developed TB around the world, up from 8.6 million in 2012, the WHO said.

However, the number of people dying from TB continued to decline, it added.

TB campaigners said that one of the biggest problems in tackling the deadly disease was gauging how many people were affected.

About 1.5 million people had died in 2013 from TB, including 360,000 people who had been HIV positive, the WHO said in its Global Tuberculosis Report 2014. And in 2012, there had been 1.3 million tuberculosis deaths.

Myth Busted: Ancient Humans May Not Have Been Redheads

Live Science Tanya Lewis 22 October 2014

Ancient humans found with red hair weren’t necessarily redheads in life, but may have acquired their carrot tops after death, a new study finds.

The findings are not only important for archaeology, but also for conservation efforts and forensic investigations, according to the study published Oct. 21 in the journal Proceedings of the Royal Society B.

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