Category Archives: Clinical pathology

Includes news relating to lab diagnosis of medical conditions.
Discipline groups are Microbiology, Immunology, Anatomical Pathology including cytopathology (cancers etc), Chemical pathology, Haematology and Laboratory management.
EXCLUDES imaging technologies.

ASM issues lab guidelines for handling Ebola specimens

BioPrepWatch Paul Tinder 27 August 2014

The American Society for Microbiology issued interim laboratory guidelines on Thursday for handling and testing specimens from cases or suspected cases of hemorrhagic fever viruses (HFV) like Ebola.

The guidelines follows the recent interim guidance issued by the Centers for Disease Control and Prevention for specimen collection, transport, testing and submission for patients with suspected Ebola virus disease infection.

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ASM Interim Laboratory Guidelines for Handling/Testing Specimens from
Cases or Suspected Cases of Hemorrhagic Fever Virus (HFV)

Delayed diagnosis and inability to access best treatment mean ovarian cancer kills more in rural areas

Courier Mail Janelle Miles 1 September 2014

WOMEN living in rural Australia are at higher risk of dying from ovarian cancer than their city counterparts.

Researchers analysed medical records of more than 1100 Australian women diagnosed with ovarian cancer in 2005, finding just 35 per cent lived for five years after diagnosis.  Lead researcher Susan Jordan, of the QIMR Berghofer Medical Research Institute, said those living in regional and remote areas of the state were about 20 per cent more likely to die during the study than those in urban areas.

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Researchers identify tests to diagnose invasive aspergillosis with 100 percent accuracy

(Elsevier Health Sciences 13 August 2014) The fungal infection invasive aspergillosis can be life threatening, especially in patients whose immune systems are weakened by chemotherapy or immunosuppressive drugs. Despite the critical need for early detection, IA remains difficult to diagnose. A study in The Journal of Molecular Diagnostics compared three diagnostic tests and found that the combination of nucleic acid sequence-based amplification and real-time quantitative polymerase chain reaction detects aspergillosis with 100% accuracy.

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Revolutionary handheld DNA diagnostic unit allows lab-quality analysis in the field

(University of Otago 25 August 2014) A revolutionary handheld and battery-powered DNA diagnostic device invented at New Zealand’s University of Otago is poised to become a commonly used field tool for rapidly detecting suspected viruses or bacteria in samples while also determining the level of infection. It  also has many other potential uses, such as border security, forensics or environmental monitoring.

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Biomarker in an aggressive breast cancer is identified

(Northwestern University 19 August 2014) Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a protein called STAT3, provides a smart target for new therapeutics designed to treat this often deadly cancer. Using patient data from The Cancer Genome Atlas, the researchers used bioinformatics techniques and found that a small number of genes are activated by STAT3 protein signaling in basal-like breast cancers but not in luminal breast cancers.

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A highly sensitive microsphere-based assay for early detection of Type I diabetes

(World Scientific 12 August 2014) A rapid, highly sensitive assay technique for measuring type 1 diabetes mellitus marker autoantibodies can provide better temporal resolution of disease onset and progression.

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Hospital unveils automated clinical laboratory

The Catholic Transcript Online [Connecticut] Jack Sheedy 21 August 2014

St Francis Hospital has a new 4,200-square-foot, fully automated clinical laboratory system.  Billed as the first fully automated lab in North America, the clinical laboratory was designed to replace older equipment, improve efficiency, reduce costs and improve turnaround time.  It consolidates all major testing disciplines including chemistry, immunochemistry, hematology and coagulation.

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