Tag Archives: Laboratory animals

Adelaide University study finds immune cells might boost breast cancer risk

ABC News 20 September 2013

Researchers have found immune cells which protect the body from disease could also increase the risk of breast cancer.
Laboratory studies on mice, at the University of Adelaide, have found immune cells in the breasts, known as macrophages, change in function during the menstrual cycle.

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Animals in research: rats

The Conversation 18 September 2013

Our series, Animals in Research, profiles the top organisms used for science experimentation. In this instalment, we look at the original lab rats: Rattus norvegicus.
Rats have a long history in medical research: they were the first mammalian species specifically domesticated to be used in the laboratory.

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New code, same suffering: animals in the lab

ABC News  Merkes and Buttrose Aug 1, 2013

The NHMRC has released a new edition of their code on the welfare of animals used in scientific research. But there are few significant changes, and without any avenues for true accountability, the code works more for the benefit of research than the animals it is meant to protect, writes Monika Merkes and Rob Buttrose.
A new edition of the Australian code for the care and use of animals for scientific purposes was released on July 23, 2013 by the National Health and Medical Research Council (NHMRC), updating the previous 2004 version.

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Link to  new ed. NHMRC code

Animals in research: benefits, ethics and assessment

The Conversation Gavan McNally 9 July 2013

Research involving non-human animals remains poorly understood and highly emotive.

Studies in non-human animals have led to countless  treatments. Some examples include penicillin vaccinations, medications for high blood pressure, neuroprotective agents, deep brain stimulation for Parkinson’s disease, antidepressants, analgesics, cardiac defibrillators, and pacemakers. These alleviate pain and suffering. They extend lifespans.

Along the way to these successes were numerous discoveries in basic science. The knowledge from basic research was central to advancement but appeared to add little to solving the pressing medical problems of the day. There were many blind alleys and apparent failure.

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Animals in research: mice

The Conversation Micahel Dobbie, Ruth Arkell, Stuart Read 27 May 2013

Our series, Animals in Research, profiles the top organisms used for science experimentation. Here, we look at a species familiar to most: Mus musculus, or the mouse.

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Scientist smells a rat that proves to be a hit

Sydney Morning Herald Bridie Smith 28 May 2013

When Bill and Melinda Gates put out the call for a suitable animal to test drugs for the debilitating river blindness disease, geneticist Warwick Grant knew he had just the thing.  Enter the Australian bush rat. Common in heathland areas of Victoria and NSW, the bush rat carries a parasite long overlooked by scientists.

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Animals in research: C. elegans (roundworm)

The Conversation Hannah Nicholas 20 May 2013

One species of worm – Caenorhabditis elegans – has contributed more to medical science in the past few decades than you might think possible.  More commonly referred to simply as “the worm”,  C elegans is now the subject of research in hundreds of laboratories around the globe, including, at my count, at least ten labs in Australia.

Animal experiments under the microscope

Radio National Hagar Cohen 5 May 2013

The process of approving the use of animals in scientific experiments is in crisis, with animal welfare and scientific members on key ethics committees at loggerheads.

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Eggs created from mice stem cells, providing research avenue for human reproduction

The Australian AAP October 05, 2012

EXPERIMENTS which turned mice stem cells into viable eggs used to create offspring via in vitro fertilisation would be fraught with scientific and ethical hurdles in humans, Australian researchers say.
The findings, by Japanese researchers and published in the journal Science Express, showed eggs created from the mice stem cells could be fertilised and transplanted into female mice who gave birth to newborn pups.
But Australian researchers warned that although the findings showed it might be possible to create eggs from human stem cells in the same way, this was not an option at present.

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Humane drug test project welcomed

Courier Mail John von Radowitz AAP 25 July 2012

A $A68 million research project could see future generations of drugs tested on “organ chips” that mimic different parts of the human body.  As well as improving and speeding up drug development, the move could prevent the suffering and death of many thousands of laboratory animals.

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