Tag Archives: Laboratory animals

Ebola virus: Genes ‘play significant role in survival’

BBC News

Genetic factors could play an important role in whether people survive the Ebola virus, say US scientists.
A study of mice infected with the virus found they showed a number of different symptoms, with 19% remaining unaffected by the disease.
This could explain why some people recover from the illness while others die in pain, the scientists said.
Their study is published in the journal Science.
Scientists from the universities of Washington and North Carolina, and the National Institute of Health in Montana, examined mice they had infected with the same species of Ebola virus causing the current outbreak in West Africa.

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Link to Science abstract

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Breath test for TB developed

BBC News

Researchers have developed the first breath test for TB in the laboratory.
It provides rapid information on drug resistance that takes up to six weeks using standard methods, US scientists report in the journal, Nature Communications.
The bacteria emit a unique gas signature within 10 minutes of exposure to an inhaled antibiotic in rabbits.

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Link to article abstract in Nature Communications

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Adelaide University study finds immune cells might boost breast cancer risk

ABC News 20 September 2013

Researchers have found immune cells which protect the body from disease could also increase the risk of breast cancer.
Laboratory studies on mice, at the University of Adelaide, have found immune cells in the breasts, known as macrophages, change in function during the menstrual cycle.

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Animals in research: rats

The Conversation 18 September 2013

Our series, Animals in Research, profiles the top organisms used for science experimentation. In this instalment, we look at the original lab rats: Rattus norvegicus.
Rats have a long history in medical research: they were the first mammalian species specifically domesticated to be used in the laboratory.

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New code, same suffering: animals in the lab

ABC News  Merkes and Buttrose Aug 1, 2013

The NHMRC has released a new edition of their code on the welfare of animals used in scientific research. But there are few significant changes, and without any avenues for true accountability, the code works more for the benefit of research than the animals it is meant to protect, writes Monika Merkes and Rob Buttrose.
A new edition of the Australian code for the care and use of animals for scientific purposes was released on July 23, 2013 by the National Health and Medical Research Council (NHMRC), updating the previous 2004 version.

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Link to  new ed. NHMRC code

Animals in research: benefits, ethics and assessment

The Conversation Gavan McNally 9 July 2013

Research involving non-human animals remains poorly understood and highly emotive.

Studies in non-human animals have led to countless  treatments. Some examples include penicillin vaccinations, medications for high blood pressure, neuroprotective agents, deep brain stimulation for Parkinson’s disease, antidepressants, analgesics, cardiac defibrillators, and pacemakers. These alleviate pain and suffering. They extend lifespans.

Along the way to these successes were numerous discoveries in basic science. The knowledge from basic research was central to advancement but appeared to add little to solving the pressing medical problems of the day. There were many blind alleys and apparent failure.

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Animals in research: mice

The Conversation Micahel Dobbie, Ruth Arkell, Stuart Read 27 May 2013

Our series, Animals in Research, profiles the top organisms used for science experimentation. Here, we look at a species familiar to most: Mus musculus, or the mouse.

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